Melissa & Joey: A half-hour comedy that follows Mel, the grown-up former wild child of a political family, who is now a local politician herself. When her sister ends up in prison and her brother-in-law flees after a scandal hits, Mel must take responsibility for her niece and nephew. Help comes in the unlikely form of Joe, who moves in and becomes the family’s manny.
Mel and Joe get into a property dispute with their neighbor; Ryder films a PSA starring Lennox.
Joe gets Ryder in trouble with his teacher; Mel sneaks Lennox into an 18-and-over concert.
Mel contemplates her relationship with George. Ryder meets Holly's parents.
Mel's father returns to lobby for a bill Mel is against; Lennox's poems garner the attention of a classmate.
Mel's new younger boyfriend George throws a party for Mel to meet his friends. Meanwhile, Joe confronts his ex-wife for going on a date at their spot on their anniversary.
Mel starts a romance with a younger man; Lennox challenges a classmate to be the editor of the school blog.
Mel feels the pressure to find someone after her last single friend gets engaged.
Mel volunteers Joe for a school charity auction but the winner of the auction may have ulterior motives.
Lennox is approached in a mall to be a model but has to persuade Mel for permission; Joe helps Ryder ask a girl out.
Mel surprises Joe at his college reunion, pretending to be his girlfriend after discovering he's embarrassed about his life.
A dinner between Mel, a Japanese businessman, and Joe, who acts as a translator, turns awkward; Lennox and her nemesis are forced to work on a project together.
Sparks fly between Joe & Mel’s personal trainer. Lennox tries to just be friends with Beckett even though she has a crush on him.
Joe's ex-wife wants to rekindle their relationship; Lennox works on her popularity.
After hearing spooky noises coming from the attic, Mel discovers her brother-in-law, Lewis Scanlon, has been hiding there.
Lennox dates the Mayor's son, who may not be the good influence Mel thinks he is.
Mel agrees to dance with a dancer from "Dancing with the Stars" at a charity event.
Joe dates a TV reporter working on a human interest story about Mel's life.
Mel starts to question Joe's intentions and installs a nanny cam to spy on him.
Mel disapproves of Lennox's new "bad" boyfriend though Mel dates a bad boy herself.
Joe tries to get his belongings back from his ex-wife; Mel dates a man with ulterior motives; Lennox tries to make friends.