Melissa & Joey: A half-hour comedy that follows Mel, the grown-up former wild child of a political family, who is now a local politician herself. When her sister ends up in prison and her brother-in-law flees after a scandal hits, Mel must take responsibility for her niece and nephew. Help comes in the unlikely form of Joe, who moves in and becomes the family’s manny.
Joe tries to take his slowly moving relationship to the next level. Zander and Ryder start a graphic novel.
Mel reconnects with a childhood friend, and Lennox learns that her blog sponsor uses unfair labor practices.
Joe ruins Mel and Austin's romantic weekend plans, and Ryder is stuck studying with Leland.
Austin does not want to have children, Joe is confused by his new girlfriend, and Lennox works on her college essay.
Mel and Joe learn that Lennox and Zander have taken their relationship to the next level, while Ryder struggles with his new "bad boy" reputation.
Mel and Joe co-host "Good Morning, Toledo" and become a hit when they bicker over personal family details.
Mel invites her new suitor to stay at her place; Lennox struggles with her new internship.
Joe and Mel become cat burglars to reclaim Mel's personal item that was accidentally sold; Lennox's pen pal wants to meet her after his release from jail.
Joe works out an alternative payment plan when he begins dating the mom (Krista Allen) of one of his students.
Since Joe never got around to telling "Nona" he and Tiffany got divorced, he's forced to beg Mel to pretend to be his trampy ex.
Mel is excited to spend Christmas with her sister, Meredith (Jaime Pressly), who is on furlough from prison.
Joe rushes home to tell Mel that he has feelings for her but he’s shocked to find Austin has shown up and wants to give his relationship with Mel another try.
After winning an 8-course dining experience in a raffle, Mel decides to preemptively join an exercise boot camp to lose weight before she gorges on the gourmet meal.
Mel and Joe become friends with another couple, but Mel puts the relationship in jeopardy when she spills a vital secret.
Mel is on Joe’s side when he’s involved in a hit and run, until she discovers the other driver is her hairdresser.
Joe tries to help his single friend get back in the dating game but ends up finding himself in hot water with Mel.
Mel’s father accidentally sends a racy photo to everyone involved in her campaign.
Joe inherits his Nona Sophia's ugly chair and can’t wait to finally add a piece of his life into Mel’s home.
Mel is unsure if she should share the news her doctor gives her with Joe.
Mel plans the perfect wedding for her friend. When it is called off, she considers keeping all the flowers, catering and venue for her and Joe.
Mel and Joe try a little too hard to prove they have the perfect relationship.
It’s Mel and Joe’s big day. But first they need to survive the bachelor parties, love triangles and unexpected confessions.