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Comedian Damon Wayans brings his unique brand of humor to "My Wife and Kids." Wayans plays Michael Kyle, a self-made entrepreneur who dreams of a simple, traditional life in Connecticut. But that dream is pushed further and further from reach by his wife, Jay (Tisha Campbell-Martin), and their three kids -- Michael aka "Junior," Claire, and Kady.

Michael and Jay do their best to keep their sanity through family crises such as their kids' break-ups and Junior's unexpected fatherhood (little Junior!). But through all the problems and distractions, the Kyles manage to put family first and teach their kids meaningful life lessons.

Damon hails from the well-known Wayans family, which also includes Keenen Ivory Wayans, plus Marlon, Shawn, and their sister, Kim. The show drew some major guest stars, including Michael Jordan and Shaq, plus Keenen, Raven-Symone, Gary Coleman, and even Wayne Newton(!).